Klinoril

《英文msh词典》Klinoril
[入口词] Klinoril
[主题词] Sulindac
[药动学] Cyclooxygenase Inhibitors
[英文释义] A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically,the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.