Receptor,neu

《英文msh词典》Receptor,neu
[同义词] Receptor,neu
[主题词] Receptor,erbB-2
[中文释义] 受体,neu
[英文释义] A cell surface protein-tyrosine kinase receptor that is found to be overexpressed in a significant number of adenocarcinomas. It has extensive homology to and can heterodimerize with the EGF receptor (RECEPTOR,EPIDERMAL GROWTH FACTOR),the erbB-3 receptor (RECEPTOR,ERBB-3) and the erbB-4 receptor. Activation of the erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB receptor family members.