hdac

hdac

美 　英

• 网络组蛋白去乙酰化酶；组蛋白脱乙酰基酶；组蛋白脱乙酰化酶

例句

In summary, curcumin inhibited the HAT activity and has no effect on HDAC activity in in vitro assays.

以上结果表明，姜黄素在体外具有HAT抑制活性，而对HDAC活性无影响。

However, existing HDAC inhibitors can exhibit low potency, lack of selectivity, and poor pharmacokinetic or toxicity profiles.

但现有HDAC抑制剂效度低、缺乏选择性、药代动力学或毒性特征较差。

The object is to find a novel pharmacological activity of a compound capable of inhibiting an HDAC.

本发明的目的在于发现具有HDAC抑制作用的化合物的新的药理作用。

We found that the HDAC inhibitors drastically improved the learning ability of our mouse model.

我们发现，HDAC抑制剂大大提高了我们的小鼠模型的学习能力。

Objective: To improve the synthetic procedure of the histone deacetylase (HDAC) inhibitor SAHA.

目的：改进组蛋白去乙酰化酶抑制剂SAHA的合成工艺。

HDAC inhibitors block the removal of these acetyl groups.

HDAC抑制剂阻断了去乙酰基化过程。

HDAC removes certain chemicals, called acetyl groups, from a wide range of proteins.

HDAC可以从很多蛋白质中去除一种叫做乙酰基的化学结构。

HDAC activity plays a key role in the regulation of gene expression, and HDAC is a clinically validated cancer target.

HDAC活性在基因表达的调控中发挥关键作用，HDAC是一种经过临床验证的癌症靶标。

In addition, the activity of non-histone proteins can be regulated through HDAC-mediated hypo-acetylation.

此外，活动的非组蛋白可以调节通过HDAC介低乙酰化。

The present invention relates to hydroxamic acid derivatives that are inhibitors of histone deacetylase (HDAC).

本发明涉及作为组蛋白脱乙酰基酶（HDAC）抑制剂的异羟肟酸衍生物。

The effect of the HDAC inhibitor and the anti-cancer agent may be additive or synergistic.

HDAC抑制剂和抗癌药的作用可能是加和性或协同的。

HDAC Heater, Defroster, Air Conditioning Assembly

加热器，除霜器及空调总成

Structure based virtual screening of HDAC inhibitors

基于结构的组蛋白去乙酰化酶抑制剂虚拟筛选

Sweatt's lab has already studied a group of experimental drugs called HDAC inhibitors

斯韦特的实验室已经研究了一组叫做HDAC抑制剂的试验性药物

The role of HDAC 2 in pressure overload-induced cardiac hypertrophy of rat

组蛋白脱乙酰基酶2在大鼠心肌肥大中的作用