kinases

kinases

 英

  • 网络依赖性激酶;激酶学;蛋白质激脢

例句

However, its structure may be similar to that of another class of enzymes called DNA-dependent kinases.

但是结构可能非常相似叫做DNA依赖激酶一类别的

So people will try and get some sort of gene-based test to measure the expression-mutation of these kinases.

因此人们尝试取得一些基因水平测试蛋白激酶突变表达方法

Kinases that work through different pathways, however, now seem to hold more potential.

激酶通过不同途径作用但是现在看来可能性可能更多

We also describe recent advances in understanding how the regulatory protein kinases control the progress of the initiation reaction.

我们描述理解调控蛋白质激酶如何控制起始反应过程最新进展

It has been known for at least 20 years that growth factors induce the internalization of cognate receptor tyrosine kinases (RTKs).

据悉至少20生长因子诱导内在同源受体酪氨酸激酶受体)。

Histidine kinases are widely existed in higher plants and are important components of two-component signal transduction systems.

组氨酸激酶高等植物广泛存在组分信号系统重要元件

Until now it was assumed that control of even distribution of chromosomes was only monitored by the checkpoint kinases in the kinetochore.

直到现在我们一直认为染色体正确分配控制检测激酶监控

Tyrosine kinases from the vascular endothelial growth factor and epidermal growth factor receptor families are the most pursued targets.

酪氨酸激酶血管内皮生长因子表皮生长因子受体家庭追求目标

Accordingly, the researchers have proved that these checkpoint kinases also exist alongside the centrosome and perform their function there.

由此科学家证实这些检测激酶同样存在细胞中心附近发挥他们作用

Phosphorylation enzymes called protein kinases can attach a phosphate group to proteins that may be inactive enzymes.

作用称为蛋白激酶可以依附那些已经含有磷酸盐组群蛋白质

Protein tyrosine kinases play an important role in signal transduction pathways in regulating a number of cellular functions.

蛋白质酪氨酸一系列细胞活动信号转导途径重要作用

To fully exploit the potential of kinases as drug targets, novel strategies for the efficient discovery of inhibitors are required.

充分利用潜力激酶作为药物靶点战略有效发现抑制剂必需

Mitogen-activated protein kinases mediate the oxidative burst and saponin synthesis induced by chitosan in cell cultures of Panax ginseng.

活化蛋白激酶介导乙酰诱导人参细胞迸发皂苷合成

However, few tyrosine kinases have been shown to have a well-defined pathogenetic role in lymphomas .

然而,,很少酪氨酸激酶淋巴瘤发病比较明确作用

Protein kinases comprise approximately 2 percent of the human genome, and are important anti-cancer drug targets.

蛋白质激酶人体基因组百分之二重要抗癌药物

SAP regulates signal transduction of the SLAM-family receptors by recruiting SRC kinases.

SAP调节信号转导斯拉姆家庭招募钢骨混凝土受体激酶

Protein tyrosine kinases have emerged as crucial targets for therapeutic intervention in cancer.

蛋白酪氨酸激酶成为重要目标干预治疗癌症

The present invention relates to compounds of formula (I) useful as inhibitors of protein kinases, particularly of JAK family kinases.

发明涉及可用蛋白激酶特别是JAK家族激酶抑制剂I化合物

The checkpoint kinases in cancer cells are frequently modified or present in incorrect quantity ratios.

癌症细胞检测激酶常常修改或者数量出现异常

Recent studies have revealed that the TAM receptor protein tyrosine kinases--TYRO3, AXL and MER--have pivotal roles in innate immunity.

最近研究表明受体蛋白酪氨酸激酶-TYRO3,AXL美林-关键作用先天免疫

The activity of cyclin-dependent kinases (CDKs) on specific targets mediates the temporal regulation of plant cell cycle transitions.

活动细胞周期依赖性激酶激酶介导具体目标时间调节植物细胞周期转换

The action of BMP is mediated through receptor kinases and transcription factors called Smads that regulate the expression of target genes.

BMP作用通过受体激酶称作Smad转录因子介导Smad调整基因表达

Casein kinases are critical in cell division and differentiation across species.

酪蛋白激酶许多物种细胞分裂分化过程都有重要作用

The largest group of kinases are Protein kinases, which act on and modify the activity of specific proteins.

蛋白激酶数量最多一类激酶作用修饰特定蛋白活性

DYRK1A is the first member of a novel subfamily of protein kinases with dual specificity.

DYRK1A第一个成员亚科一种新型蛋白激酶异性

However, developing such drugs has been hampered by lack of detailed understanding of how the Cdc25s fit with their associated kinases.

但是缺乏cdc25s与其相关激酶契合详细了解限制药物开发

Inhibiting BCRABL tyrosine kinases can impede the growing progress of tumors.

抑制BCRABL酪氨酸激酶有效抑制肿瘤生长

In addition, because Sutent inhibits multiple kinases, it possesses activity against multiple types of tumors.

由于sutent能抑制多种激酶所以具有多种肿瘤活性

Kinases are protein switches that activate other proteins by adding a phosphate group to them via a process called phosphorylation.

激酶蛋白开关它们通过一个称为磷酸化过程磷酸基团结合其他蛋白激活这些蛋白

Inhibiting BCR-ABL tyrosine kinases can impede the growing progress of tumors.

抑制BCR-ABL酪氨酸激酶有效抑制肿瘤生长

Progression through the cell cycle is regulated by cyclin-dependent kinases (CDKs).

级数通过细胞周期细胞周期依赖性激酶激酶)。

Plants use receptor-like kinases (RLKs) to transduce extracellular signals into the cell.

电厂使用受体激酶激酶传感器信号进入细胞

Abnormal expression of aurora kinases usually lead to numerous abnormalities in cell mitosis.

异常表达极光激酶往往导致细胞有丝分裂过程出现大量异常现象

Tyrosine kinases are involved in the pathogenesis of most cancers.

酪氨酸激酶参与大部分肿瘤发病

Cyclins regulate the cell cycle by binding to and activating cyclin-dependent kinases (Cdks).

细胞周期调控细胞周期结合激活细胞周期依赖性激酶激酶)。

This paper introduces the first, second and some new BCRABL tyrosine kinases inhibitors.

本文介绍第一、二以及新近开发BCRABL酪氨酸激酶抑制剂

Both tasocitinib and Incyte's drug, INCB028050, target Janus kinases, which mediate signalling by immune-system proteins called cytokines.

无论tasocitinibIncyte药物,INCB028050,目标直指激酶通过一种叫做细胞因子免疫系统蛋白介导信号

But imatinib is known to cause heart problems in some people because it also switches off tyrosine kinases in the ABL family.

伊马替尼众所周知导致心脏问题一些因为开关小康酪氨酸激酶abl家庭

Effect of simvastatin on myocardial hypertrophy and expression of extracellular signal-regulated kinases in spontaneously hypertensive rats

高血压大鼠心肌肥厚细胞信号调节激酶影响

Gene Expression and Activity Regulation of Two Calmodulin Binding Protein Kinases in Tobacco Seedling

烟草幼苗钙调素结合蛋白激酶活性调节基因表达