mirna

mirna

美 　英

• n.【女名】女子名
• 网络微小核苷酸；核糖核酸；微小核糖核酸

英汉解释

n.	1. 【女名】女子名

例句

A number of miRNA genes were shown to be located in fragile regions of the human genome that are associated with cancer 8.

研究结果证实，许多microRNA基因存在于那些与癌症有关的人类基因组脆弱区域。

If the miRNA levels were too high or too low, the gene would not switch on, and the cell would not be killed.

如果miRNA级别太高或者太低，这种基因就不会被激活，当然细胞也不会被杀死。

However, if a miRNA biomarker fingerprint can be established, a more accurate assessment would be more likely.

然而，如果一个microRNA指纹库得以建立，更准确的评估将变得可能。

The mature miRNA is incorporated into an RNA-induced silencing complex that binds to a target messenger RNA (mRNA).

成熟microRNA与目标mRNA结合，形成了RNA诱导的基因沉默复合体。

A sera-miRNA fingerprint was determined for colorectal cancer as well.

血清microRNA指纹同样能很好地诊断结肠癌。

MicroRNAs(miRNA) are a new class of noncoding RNAs, which are encoded as short inverted repeats in the genomes of animals and plants.

微RNA是新发现的一类非编码RNA分子，在动植物细胞中广泛表达，它的基因是短的反向重复序列。

This binding activity allows microRNAs to silence the expression of select genes in a targeted manner.

这种结合活性使得miRNA得以定向沉默目标基因。

Kaplan-Meier survival curves were constructed using mean miRNA expression (high vs low) as threshold and compared by log-rank analysis.

平均微RNA表达水平（高表达vs低表达）作为阈值形成卡普兰-迈耶存活曲线与时序分析形成的阶梯曲线加以比较。

Through various techniques, numerous groups have gone on to show that different cancer types have distinct miRNA profiles.

应用各种不同的技术，许多研究小组一直在试图寻找不同癌症的特异性microRNA表达谱。

Meanwhile, these studies show that analyzing miRNA levels in serum is a promising area for identifying biomarkers of cancer.

同时，这些研究也证实，血清microRNA的测定是一个检测癌症生物学标志物很有前途的领域。

Therefore, their stability makes miRNA levels well suited for being tested in patient samples.

因此，它们的稳定性使得其实际值与在病人身上得到的测试值吻合的很好。

The study examined human pancreatic tumor tissue and compared it to nearby normal tissue and control tissue for levels of microRNA (miRNA).

该研究检测比较了人类胰腺癌组织与周围的正常组织和对照组织中小分子RNA（miRNA）水平。

The special gene would turn on in the presence of miRNA levels that match the HeLa profile.

这种特殊的基因能够在miRNA级别与HeLa特征相匹配时被激活。

This microRNA cluster could represent a new therapeutic target for treating tumors caused by Rb deficiency.

这种miRNA簇可以为治疗Rb缺失引致的肿瘤提供新的靶点。

More recent research has shown that miRNAs also play an important role in cancer.

最近的研究已经表明miRNA也在癌症中发挥重要作用。

Scientists have now identified more than 470 different miRNAs in humans.

科学家们目前已经在人体内发现了470多种不同的miRNA。

The first serum-miRNA biomarker discovered was miR-21. Lawrie et al.

第一个被发现的血清microRNA标志物是miR-21。

Each evening when I arrived home, Mirna asked, "Has he come back, Daddy? "

每天晚上，在我到家时，米娜总是要问：“爸爸，它回来了吗？”

It also means that a test based on miRNA levels might help diagnose pancreatic cancer.

这也意味着基于miRNA水平的检查可能有助于胰腺癌的诊断。

malignant cell transformation; miRNA;

细胞恶性转化；