ranolazine

ranolazine

美 　英

• 网络雷诺嗪；崭新抗心绞痛药物；雷诺拉嗪

例句

Although several pharmacological activities of ranolazine have been described, the precise way the drug works is not fully understood.

尽管已经说明了雷诺嗪的一些药理活性，但是该药的确切作用机制仍未完全了解。

Conclusion Ranolazine can inhibit the fast sodium channel current in rabbit atrial myocytes and indeed has a use-dependent effect.

结论雷诺嗪对兔心房肌细胞快钠电流有一定的抑制作用，其存在使用依赖性阻滞作用。

The FDA also warned that use of ranolazine is contraindicated in patients with clinically significant hepatic impairment.

美国食品和药物管理局还警告说，雷诺嗪不适于临床诊断为肝损害的患者使用。

For patients taking moderate CYP3A inhibitors, ranolazine dosing should be limited to 500 mg twice daily.

患者在服用中度CYP3A抑制剂时，雷诺嗪剂量应限制在500mg内，每天两次。

METHODS Ranolazine was synthesized by using 2, 6-dimethylaniline and guaiacol as the starting material fellewed by 4 step reactions.

方法以2,6-二甲基苯胺、愈创木酚为原料，经酰化、烃化等4步反应制得雷诺嗪。

Chiral Separation of Ranolazine Hydrochloride Enantiomers by Reversed- phase High Performance Liquid Chromatography

盐酸雷诺嗪对映体的反相高效液相色谱手性分离

Direct chiral separation of racemic ranolazine by high performance liquid chromatography with chiral stationary phase

高效液相色谱手性固定相法直接拆分外消旋雷诺嗪

Improved synthesis of a novel antianginal agent ranolazine

新型抗心绞痛药物雷诺嗪的合成工艺改进

Ranolazine Improves Exercise Tolerance in Chronic Angina

雷诺嗪可改善慢性心绞痛患者的运动耐量

Study on Synthesis Process of Ranolazine

雷诺嗪的合成工艺研究

Long-term toxicity of ranolazine in rats

雷诺嗪对大鼠的长期毒性试验