kinase
美 [ˌeɪz] 
英 ['kɪneɪs]
- n.【生化】激酶
- 网络蛋白质激酶；磷酸化酵素；磷酸激酶
英汉解释
英英解释
例句
HHMI researchers have now learned that this pairing causes a physical change in the shape of the kinase domain.
霍华德•休斯医学研究所的研究人员现已经得知，这种配对导致了激酶结构域形状上的物理变化。
This Review provides a broad overview of some of the approaches currently used to discover and characterize new kinase inhibitors.
本次审查提供了一个广泛的概述了一些目前使用的方法和特点，发现新的激酶抑制剂。
The peptide can be directed to any region of the protein kinase C isozyme, and in one embodiment, is directed to the V5 domain.
所述肽可以针对蛋白激酶C同工酶的任何区域，并且在一个实施方案中，针对V5结构域。
Genistein, the tyrosine kinase inhibitors, plays the effect by an inhibition of tyrosine phosphorylation.
Genistein是酪氨酸激酶的非特异性抑制剂，通过抑制酪氨酸的磷酸化而发挥作用。
The Singaporeans' kinase (win at all costs) negotiating style does them few favours in a region where saving face is important.
新加坡人那种“怕输”（为了达到目的而不择手段）的谈判方式使得他们几乎没有什么朋友。
When wheat plants allowed to become deficient in potassium, pyruvate kinase activity increased.
当小麦植株令其缺钾时，丙酮酸激酶活性随之升高。
Rudolph initially knew the kinase's and phosphatase's general topographies as well as the locations of their active sites.
Rudolph起初知道激酶和磷酸酶总拓朴图以及活性位点的位置。
Objective To investigate the expression of focal adhesion kinase in peripheral blood of colorectal cancer and its clinical significance.
目的探讨大肠癌患者外周血淋巴细胞粘着斑激酶的表达及其临床意义。
KIT protein is expressed in SCLC, and its kinase activity has been implicated in the pathophysiology of many tumours, including SCLC.
KIT蛋白在小细胞肺癌中表达，它的激酶活性与许多肿瘤的病理生理学都有联系，包括小细胞肺癌。
The glucose role is independent and thus unaffected by turning off the kinase-activated growth signals, the researchers found.
研究者们发现，葡萄糖的作用是独立的，因此关闭酪氨酸激酶激活的生长信号通路并不会对葡萄糖产生影响。
If STI571 inhibits the BCR-ABL kinase so effectively, what is the result of its inhibition of the ABL kinase in normal cells?
如果STI571可高效地抑制BCR-ABL激酶活性，那它对正常细胞的ABL激酶的抑制会产生什么结果呢？
Protein kinase C(PKC) is the main signaling molecule of the diacylglycerol dependent protein kinase C signal transducing system.
蛋白激酶C（PKC）是甘油二酯依赖的PKC信号转导系统的主要信号分子。
Focal-adhesion kinase (FAK) is an important mediator of growth-factor signalling, cell proliferation, cell survival and cell migration.
焦点粘附激酶（斑）是一个重要的调停人的生长因子信号，细胞增殖，细胞存活和细胞迁移。
In the first set of experiments, the researchers demonstrated that the kinase domain of EGFR is normally maintained in the off state.
在试验的第一阶段，研究者证明，EGFR的激酶结构域在通常情况下处于关闭的状态。
The protein, known as AMP-activated protein kinase or AMPK, controls metabolic decisions of cells.
这种蛋白即是AMP活化蛋白激酶（AMPK），它控制着细胞能量代谢的关键。
Isoflavone . Inhibitor of EGFR tyrosine kinase, blocking phosphatidylinositol turnover.
异黄酮类。抑制EGFR酪氨酸激酶。阻断磷脂酰肌糖的翻转。
Objective To investigate the change of serum creatine kinase (CK) level and its clinical significance in acute urticaria.
目的探讨急性荨麻疹患者血清肌酸激酶水平的变化及其临床意义。
The extracellular signal-regulated kinase(ERK) is an important member of mitogen-activated protein kinase(MAPK) family.
细胞外信号调节激酶是丝裂原激活蛋白激酶家族的重要成员。
The insulin may suppress the protein kinase directly, the promotion activation glycogen enzyme production, increases the glycogen synthesis.
胰岛素可直接抑制蛋白激酶，促进活化型糖原合成酶的生成，增加糖原合成。
Heart rate, serum creatine kinase, testosterone, cortisol, blood urea, glutamine etc serve as markers for the diagnosis of overtraining.
诊断过度训练的常用指标有心率、肌酸激酶、血睾酮、血尿素、血乳酸、谷氨酰胺等。
They did this by engineering a virus to express the gene for the kinase, and then infected specific areas of the brain involved in memory.
他们的制作方法如下：首先制造一种病毒来表达该激酶的基因，之后感染和目标记忆相关联的大脑区域。
Polyadenylation is mediated by the phosphorylation of CPEB by Aurora, a kinase whose activity oscillates with the cell cycle.
是介导的多聚磷酸化CPEB的极光，一个激酶的活动振荡与细胞周期。
The invention provides methods for the treatment of tyrosine kinase inhibitor resistant cancers with anti-EGFR antibodies.
本发明提供了使用抗EGFR抗体治疗抗酪氨酸激酶抑制剂的癌症的方法。
But laboratory experiments suggest mutation slows the activity of a protein called casein kinase I delta (CKIdelta).
实验室的研究结果显示，这种突变使一种名为CKIdelta的蛋白质活性变差。
Mutations in GNA11 induced spontaneously metastasizing tumors in a mouse model and activated the mitogen-activated protein kinase pathway.
在小鼠模型中，GNA11突变诱导了自发转移性肿瘤，激活了丝裂原活化蛋白激酶途径。
Protein tyrosine kinase(PTK) inhibitor is one of the new targets of oncotherapy.
蛋白酪氨酸激酶（PTK）受体是肿瘤治疗的一个新靶点。
BACKGROUND: Fms-like tyrosine kinase-3 (FLT3) gene is one of the receptors for growth factors in early hematogenesis.
背景：Flt3基因是近年来发现的早期造血生长因子受体基因。
Displays cytostatic and cytotoxic activity. Inhibitor of EGFR kinase. Shows antiangiogenic activity.
显示细胞生长抑制和细胞毒活性。EGFR激酶抑制剂。有抗血管生成活性。
OBJECTIVE The antidiabetic properties of metformin are mediated through its ability to activate the AMP-activated protein kinase (AMPK).
目的二甲双胍通过激活腺苷酸活化蛋白激酶（AMPK）起到治疗糖尿病的作用。
Treatment with Tyrosine Kinase Inhibitors for Patients with Differentiated Thyroid Cancer: the M. D. Anderson Experience.
大量的临床经验：酪氨酸激酶抑制剂治疗患有分化型甲状腺癌的患者：M。D。安德森经验。
The results support the hypothesis that activated protein tyrosine kinase receptors are involved in the proliferation of glioma cells.
研究结果支持了有活性的蛋白酪氨酸激酶受体在脑胶质瘤细胞增殖有关的假设。
Objective To evaluate the relationship between glomerular protein kinase C (PKC) and renal alterations under diabetic state.
目的探讨糖尿病状态下肾小球蛋白激酶C（PKC）与肾脏改变的关系。
The inactivation and unfolding of arginine kinase by aspartic acid was studied by enzyme activity and fluorescence emission spectra.
应用酶活测定、荧光发射光谱等方法分析了精氨酸激酶在不同浓度天门冬氨酸中活性变化和去折叠动力学。
The experimental result shows: the soybean protein kinase have fight salt in plant adversity resistance, survival plays an important role.
实验结果显示：此大豆蛋白激酶具有抗盐抗旱性，在植物的逆境生存中发挥着重要的作用。
AIM: To explore the relationship of methylation status and expression of spleen tyrosine kinase (Syk) gene in colorectal cancer cell lines.
目的：探讨结直肠癌细胞中脾酪氨酸激酶基因甲基化和表达的关系。
The potency ratio to inhibit keratinocyte proliferation follows their potency to inhibit EGF receptor kinase activity in vitro.
药效比抑制角质形成细胞增殖如下其效力，抑制表皮生长因子受体激酶活性的影响。
Objective To diagnose and treat leukemia, protein tyrosine kinase (PTK) activities were studied in human blood and myelogenic cell.
目的研究人外周血与骨髓细胞蛋白酪氨酸激酶（PTK）活性，为临床诊断、治疗白血病提供基础数据。
Anti-cancer drugs that jam the enzyme, preventing its docking with the kinase, could halt cell over proliferation to treat such cancers.
干扰此酶的抗癌药物防止它与激酶对接，可以阻止细胞过度增殖，从而治疗这种癌症。
In sporophytic SI, two linked loci produce glycoprotein and a kinase that disable each other.
在孢子体自交不亲和系统中，两个连锁的基因座可以合成糖蛋白和一种让彼此失活的激酶。
Positive and negative regulation of plant pathogen defense responses has been attributed to mitogen-activated protein kinase cascades.
积极和消极的调节植物病原体防御反应是由于有丝分裂原活化蛋白激酶级联。
