epigenetic
美 [ˌepədʒə'netɪk] 
英 [epɪdʒɪ'netɪk]
- adj.外成的；具有外成性质的；【地】生于地表的；近地表生成的
- 网络表观遗传；表观遗传学；外遗传
英汉解释
英英解释
例句
But, mutagenic action is not the only mechanism of hereditary change, the epigenetic mechanism may also play an important role in it.
然而，致突变作用并不是遗传改变的唯一机制，表观遗传基础对此也具有重要作用。DNA甲基化成为外遗传的基础机制已经倍受关注。
In some cases, epigenetic changes in people seem to be passed on to subsequent generations.
在某些情况下，人类的表观遗传变异似乎会传递给后代。
Epigenetic mechanism might be associated with reduced expression of FHIT in a part cases of esophageal squamous cell carcinomas.
一部分食管癌FHIT基因表达降调则可能要归因于表遗传机制。
With epigenetic drugs, it is possible to reverse aberrant gene expression profiles associated with different disease states.
用表观药物，可能逆转与不同疾病状态相关的异常的基因表达谱。
At this time I would also like to see some effort "in the Department must live, death epigenetic" shadow.
这时我倒也仿佛看出了点“于绝处活，死而后生”的影子。
Recently, the concept that epigenetic, as well as genetic, events might be central to the evolution of human cancer is re-emerging.
最近，这一概念后生，以及遗传，事件可能是中央的演变人类癌症是重新出现。
But it's hard to tell in most natural populations whether inheritance is due to DNA sequence variation or epigenetic changes.
但在自然界大多数种群中，很难判断遗传是否源于DNA序列改变或者表观基因变异。
The nature of these reactions means epigenetic processes are susceptible to chemical intervention in a way that genetic mutations are not.
从这一过程的特性可以看出，表观遗传调控容易受到化学物质的影响，而遗传突变并不是这样。
DNA methylation is one of the most common epigenetic events occurring in human genome and is implicated in cancer.
DNA甲基化是人类基因组发生最为常见的一种表观遗传学事件，因而研究甲基化与肿瘤的关系成为当前分子生物学的热点之一。
The main cause of these problems may be attributed to the epigenetic reprogramming of somatic donor genome.
有研究认为，克隆胚胎发育障碍的一个重要的原因是供体细胞的遗传重编程不完全。
Methylation is an epigenetic modification to one's DNA that changes a gene's activity, generally reducing that activity within the genome.
甲基化作用是对DNA的后天修改，并改变基因活动，通常是在基因组内减少这个活动。
In the last decade, an increasing amount of data has pointed to a key role for epigenetic alterations in human cancer.
在过去的十年里，越来越多的大量数据指出了表观改变在人类癌症中的一个关键作用。
Methylation of cytosine residues is one of the most versatile mechanisms of epigenetic regulation.
胞嘧啶残基的甲基化是表观遗传调控的最复杂的机制之一。
One critical factor of these developmental failures of cloned embryos is the aberrant epigenetic reprogramming.
异常的表观遗传重编程是克隆胚胎发育失败的一个重要因素。
It may be that epigenetic changes could be reinforced by mutations in the DNA, making them stable and heritable in the conventional way.
也许表观基因变异会因DNA突变而得到强化，且由此变得稳定并以常规方式遗传下去。
Scientific development is pregnant with a breakthrough, epigenetic studies are pushing the genetics forward.
科学的发展孕育着突破，表遗传学研究推动着新一轮的遗传学的发展。
There is now evidence that environmental events can directly modify the epigenetic state of the genome.
现在有环境事件能够直接修饰基因组的表观遗传状态的证据。
Genomic imprinting is an epigenetic phenomenon of the monoallelic expression of genes depending on their parental origin.
基因印迹是指亲本来源不同的一对等位基因表达不同的遗传现象。
In the context of these new forms of treatment, epigenetic or transcriptional cancer therapy is clearly promising.
这篇文章主要论述这些治疗的新形式，表观遗传或者转录的癌症治疗是很有希望的。
One of the best known epigenetic factors is DNA methylation, which is a major mechanism for regulation of gene expression.
表观因子中最著名的一个是DNA甲基化，它是基因表达调控的一个主要机制。
It includes epigenetic uranium impregnations in sandstone.
它意味着外生的铀进入到砂岩中。
Epigenetic mutations confer heritable changes in gene expression that are not due to changes in the underlying sequence of the DNA.
表观遗传突变是指没有引起DNA序列变化的可遗传的基因表达改变。
DNA methylation is an important epigenetic modification which regulates a number of biological processes.
DNA甲基化作为一种重要的表观遗传修饰，调节着机体许多生物学过程。
Researchers have found that liver cells undergo epigenetic modifications that vary with the time of day.
研究人员发现肝脏干细胞分化的表观遗传修改，随白天的时间。
Epigenetic modifications are often retained when cells divide, and can sometimes be passed on to offspring.
表观遗传修饰经常在细胞分裂的时候会保留下来，并且有时会传递给后代。
Several epigenetic drugs targeting DNA methylation and histone deacetylation enzymes have been tested in clinical trials.
靶向DNA甲基化和组蛋白去乙酰化酶的几个表观药物已经在临床试验中被测试。
Epigenetic marks, such as the modifications of the histones, are also important for the specialisation of the body's cells.
表观遗传标记，例如组蛋白修饰，对于机体细胞的分化也很重要。
DNA methylation is one of the most common epigenetic events in eukaryotic cell.
DNA甲基化是真核细胞基因组最常见的一种表观遗传学修饰。
In principle, drugs could tinker with the epigenetic code to turn entire sets of rogue genes on and off .
原则上，药物可拨弄外遗传编码，进而开启或关闭整组坏基因；
Disruptions to the normal epigenetic pattern of the cell can serve as biomarkers and are important determinants of cancer progression.
中断正常的后生格局的细胞可作为生物标志物和重要的决定因素是癌症的进展。
Recently, it has been shown that germ-cells, too, are subject to epigenetic change, sometimes in response to environmental stimuli.
最近的研究显示，细菌的细胞同样受后天改变的影响，这些遗传变化有时是对外部环境刺激的反应。
The incorporation of histone variants most probably has epigenetic consequences and contributes to architectural changes in chromosomes.
组蛋白变体的合并最可能具有表观影响，并有助于染色体的结构化改变。
Aberrant DNA methylation is one of the major characteristics of tumor cells in addition to genetic and other epigenetic alterations.
DNA甲基化的异常是肿瘤细胞的主要特征之一，此外还有遗传的和其他表观上的改变。
A similar question remains for the inheritance of the epigenetic characteristics from parents to offspring.
表观遗传特性的同样问题存在于亲代和子代之间。
The methylation of histone lysine is an important covalent modification at its tails and plays a key role in epigenetic regulation.
组蛋白赖氨酸甲基化是组蛋白尾段发生的一种重要共价修饰，在基因的表观遗传转录调控中起着关键的作用。
Most epigenetic studies have been limited to a cellular context or have looked at the epigenetic effects of drugs or diet in utero.
多数表观遗传研究要么局限于细胞水平上，要么局限于药物与饮食对子宫的表观遗传效应的研究。
Overlapping epigenetic mechanisms have evolved in eukaryotic cells to silence the expression and mobility of transposable elements (TEs).
重叠的后生机制已经发展在真核细胞中的表达沉默和流动的转座因子（工商业污水附加费）。
These findings provide a mechanistic basis for developmental regulation of splicing outcome through heritable epigenetic marks.
这些发现提供了通过可遗传的表观遗传标记影响拼接的发育调控的基础。
DNA methylation, catalyzed by methyltransferases, is a normal epigenetic DNA modification approach in eukaryotic cells.
DNA甲基化由DNA甲基转移酶催化发生，是真核细胞DNA正常的表观遗传学修饰方式。
Sequencing-based approaches now allow high-resolution, genome-scale investigation of cellular epigenetic landscapes.
基于测序的方式现在允许细胞表观状况的高通量，基因组范围的研究。
Predisposition is based on interactions between the genome and environmental influences acting through epigenetic modifications.
倾向是基于基因组之间的相互作用和环境的影响通过后生修改。
